 
 
11 
 
Chapter 2 
MYOCARDIAL INFARCTION, ACUTE CORONARY 
SYNDROMES, AND CPR. 
 
Recommendations are considered Category 1B by the WMS Panel of Expert Reviewers. 
 
 
 
I. GENERAL INFORMATION: 
    Acute Coronary Syndrome (ACS), including myocardial infarction and unstable angina  
is a major cause of mortality. Chest pain is the most common reason for emergency calls 
to the US Coast Guard and is the most common reason for EMS dispatch in the US. In 
Urban areas, approximately 15% of EMS transports for chest pain are due to documented 
ACS; in more rural areas, such as Scandinavia, up to 30% of chest pain victims arriving 
to hospital by EMS transport have ACS. In the U.S., mortality from ACS rises 
proportionally with the distance a victim lives from a CCU. In the pre-defibrillator era, 
mortality from myocardial infarction was 50%. In the years after defibrillators were 
available, but before thrombolytics were routinely used, acute mortality from ACS was 
approximately 15-20%, and was improved mainly due to the routine use of aspirin, 
betablockers and nitrates.  In the post-thrombolytic era, mortality fell to 5-10%.  With 
advent of angioplasty for ACS, acute mortality in tertiary referral hospitals in the United 
States approaches 3-5% and in Europe remains 5-7%.  It is now recognized that arterial 
pathology with platelet rich thrombii and inflammed, ulcerative plaque is the same in 
unstable angina as in myocardial infarction, only the extent of coronary flow obstruction 
is different. Immediate evacuation saves lives in the setting of ACS. The quickest route to 
the hospital is the best route, even if the victim has to walk at a slow pace. Physical rest is 
preferred, but if litter transport is impossible due to terrain or lack of assistance, the 
victim should attempt slow self rescue.  Reperfusion therapy, even up to 36 hrs post 
infarction, will reduce long term mortality and complications from infarction. Death 
occurs from arrhythmias (bradycardic or tachycardic), shock (with or without pulmonary 
edema) or stroke. Even in settings far from medical help, simple measures can reduce 
mortality while evacuation is proceeding. 
 
Recognition of Acute coronary syndromes:  
·
 
Symptoms: Chest Pain with or without radiation to the arm or Jaw.   
 
Unstable angina pain will wax and wane and may be relieved by 
nitroglycerin. Pain radiating to the back or stomach suggests 
inferior MI. Myocardial Infarction pain will not be completely 
relieved by nitrates.                                                                                           
 
Nausea with both anterior and Inferior MI. When associated with 
diarrhea is usually a sign of impending shock with Inferior MI and 
represents vagal shock.