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made by the Swiss Serum and Vaccine Institute), taken every other day for four doses
(day 0, 2, 4, 6). Booster requirements for the oral vaccine has not been determined but
efficacy has been shown to persist at least 5 years. Therefore, an adequate booster will be
achieved by repeating the 4 capsule every other day regime every five years.
A new injectable vaccine produced by Pasteur Mérieux Sérums & Vaccins and
distributed in the U.S. by Connaught is the Typhim Vi polysaccharide vaccine. Studies
show a four-fold increase in antibody protection in 88 to 96% of recipients. Efficacy
studies have demonstrated protection rates from disease during exposure of 55%.
Immunization dosage is a single .5 mL injection given IM. A booster is recommended
using a single .5 mL injection every 2 years.
Yellow Fever
Immunization is required for travel to many countries in South America, Africa and Asia.
The immunization consists of one 0.5 ml injection, which confers immunity for 10 years.
It is available only at designated Yellow Fever Vaccination Centers (check your County
or State Board of Health for the nearest facility). The booster dose is the same amount
every 10 years. Approximately 5 to 10% of recipients have headache, lethargy, muscle
ache and fever that occurs 5-10 days after vaccination. This immunization must be
recorded on an International Certificate of Immunization and will not be considered valid
for 10 days from the time of injection.
