5:00 pm 6:30 pm
Registration and Welcome Reception
Gary E. Gibson, Ph.D., Weill Medical College
of Cornell University, Burke Medical
Research Institute
6:30 pm 6:45 pm
Welcome and Introduction
6:45 pm 8:15 pm
Keynotes
Session Chair: M. Flint Beal, M.D., Weill Medical College
of Cornell University
A Mitochondrial Paradigm for Metabolic and Degenerative Disease,
Cancer and Aging
Douglas C. Wallace, Ph.D., University of California at Irvine
Mitochondrial DNA Mutation in Brain Aging and Neurodegeneration:
What the Patients Tell Us
Doug M. Turnbull, Ph.D., M.D., Newcastle University
7:30 am 8:30 am
Registration and Continental Breakfast
8:30 am 10:30 am
Session I: Oxidant Actions and
Production in Cells
Session Chair: Alvaro Estevez, Ph.D., Burke Medical Research Institute
The Interaction of Superoxide and Nitric Oxide with SOD:
New Insights into the Disruption of Mitochondrial Function
Joseph S. Beckman, Ph.D., Oregon State University
Cellular Sources of Reactive Oxygen Species and the Role of
Mitochondria in ROS Metabolism and Signaling
Anatoly Starkov, Ph.D., Weill Medical College of Cornell University
Regulation of Signal Transduction by Protein Tyrosine Phosphatases
Nicholas K. Tonks, Ph.D., Cold Spring Harbor Laboratory
10:30 am 11:00 am
Coffee Break
10:30 am 1:00 pm
Session II: Evidence for Oxidant
Damage in Brains
Session Chair: John Pinto, Ph.D., Burke Medical Research Institute
Evidence of Oxidant Damage in AD Brain: Proposed Treatments
Using Antioxidants
Domenico Pratico, M.D., University of Pennsylvania, Philadelphia
Evidence of Oxidant Damage in HD Brain: Proposed Treatments
Using Antioxidants
Robert J. Ferrante, Ph.D., Boston University School of Medicine;
Bedford VA Medical Center
Oxidative Stress in Parkinson's Disease: A Mechanism of Pathogenic
and Therapeutic Significance
Serge Przedborski, M.D., Ph.D., Columbia University College of
Physicians and Surgeons
Approaches to Antioxidant Treatments
John Blass, M.D., Ph.D., Weill Medical College of Cornell University;
Burke Medical Research Institute
1:00 pm 3:00 pm
Lunch and Poster Session
3:00 pm 4:30 pm
Session III: Antioxidant Treatments
Session Chair: Arthur J.L. Cooper, Ph.D., Burke Medical Research
Institute
Mitochondria-Targeted Antioxidants in the Treatment of
Neurodegenerative Diseases
Mike Murphy, Ph.D., MRC-Dunn Human Nutrition Unit, Wellcome Trust
Cambridge, United Kingdom
Development of Mitochondria-Targeted Aromatic-Cationic Peptides
for Neurodegenerative Diseases
Hazel H. Szeto, M.D., Ph.D., Weill Medical College of Cornell University
Activation of Multiple Antioxidant Defense Genes Simultaneously
Through Activation of the Nrf2-ARE Pathway
Jeffrey A. Johnson, Ph.D., University of Wisconsin at Madison
4:30 pm 5:15 pm
Junior Investigators Session: Platform
Presentation of Three Selected Posters
Session Chair: Rajiv R. Ratan, M.D., Ph.D., Weill Medical College of
Cornell University, Burke Medical Research Institute
5:15 pm 6:45 pm
Reception and Poster Session
6:45 pm
Conference Banquet
PRELIMINARY PROGRAM
T
HURSDAY
, S
EPTEMBER
27, 2007 7:30
AM
8:15
PM
M
ITOCHONDRIA
& O
XIDATIVE
S
TRESS
IN
N
EURODEGENERATIVE
D
ISORDERS
W
EDNESDAY
, S
EPTEMBER
26, 2007 5:00
PM
9:00
PM
