19
Table 3. Estimated world-wide sales (1991) of recombined proteins which are used as
pharmaceuticals (Source: Decision Resource Inc)
Recombinant product
Estimated sales (million USD)
Erythropoietin 990
Human insulin
540
Human growth hormone
525
-Interferon
445
Tissue plasminogen activator
270
Granulocyte colony stimulating factor
255
In addition, enzyme will be useful in the synthesis of complex molecules needed in immunology,
endocrinology, intermediate metabolism, molecule genetic, and plant or insect biology. Water-soluble
synthetic targets such as carbohydrates and nucleic acids are now commonly manipulated with enzymes.
Enzymology complements both classical synthetic chemistry and biological synthetic techniques.
Enzymes are also useful in isotopic labeling, analysis and waste treatment.
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Acylnitroso Diels-Alder Cycloadduct-Derived Aminocyclopentenol". J. Org. Chem. Vol. 70, pp.
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