In order to look for accurate and objective evidence for clinical diagnosis and treatment of
acute brain failure at high altitude. 10 cases of the acute brain failure were evaluated by clinical
examination and laboratory methods. EEG_BEAP_SLSEP_TCD and Near-infrared
spectroscope (NIRS) were used to evaluate the cases. Young grade of dynamic EEG was used to
assess location and severity of disease. 6 cases were diagnosed as brain death. 3 cases
demonstrated a state of persistent vegetation. 1 case recovered consciousness after three months.
Grade I portended a more favorable prognosis. Grade III portended a poor prognosis yet still
allowed for the possibility of recovery with dynamic EEG monitoring. BAEP showed that all
cases had abnormalities, especially on V-wave. The presence of a high sharp wave of blood flow
on TCD indicated a better prognosis. However, if the concussion wave and blood flow
disappeared, the prognosis was worse. NIRS monitoring showed that all cases suffered a decline
in cerebral oxygen saturation. The lower the saturation was, the more damage was. An NIRS
reading lower than 40% portended a poor prognosis. The combination of clinical examination and
electrophysiological index can improve the accuracy of evaluation on acute brain failure.
214.
AN INVESTIGATION OF GENERAL PHYSICAL CONSTITUTION IN 1800 CHILDREN AT
MODERATE HIGH ALTITUDE. Wang Shou-Lei
1
. Dept. Child Hygiene. Qinghai Province
Women and Children Hospital, Xinning, Qinghai, R. P. C
1
.
We hypothezied that there could be an effect of high-altitude hypoxia on the physical grouth
in children. The aim of this study was to investigate the general physical constitution in children
living at moderate high altitude and compare that with children living at lower altitude. We
randomly selected the data of general physical constitution including weight, hight, body surface
area, eyesight test, dental examination and arterial oxygen saturation (SaO2) in 1800 children
with aged 7-18 yrs with a mean of 13 yrs from April to December, 2003 at an altitude of 2260m.
We also got above data of 300 children aged-matched living at 16m were as a control group. The
standard of cacotrophy was confirmed according to the diagnostic criteria of cacotrophy (NCHS)
established by WHO at the 1999. The incidences of cacotrophia, dental caries and poor visual
sight were 668 cases (37.12%), 465 cases (25.84%) and 830 cases (46.13%), respectively, in
2260m group. Whereas the incidences of cacotrophia, dental caries and poor visual sight were 49
cases (16.34%), 80 cases (26.65%) and 144 cases (48.08%), respectively in 16m group. There
was significantly different the incidence of cacotrophia between 2260m group and 16m group
(x2=49.37, p<0.01). There was significant difference in SaO2 (94.2±2.9 vs. 99.4±2.5%, p<0.01)
between 2260m group and 16m group.There were no obvious differences in the incidences of
dental caries and poor visual sight between the two groups. In conclusion, high-altitude hypoxia
and inhospitable climate and poor socioeconomic status may play major roles in promoting
cacotrophia.
215.
EXPERIMENTAL STUDY OF THE ANTI- HYPOXIC EFFECTS OF BOS MUTUS
PRZEWALSKI BLOOD IN RATS. Jia Shou-Ning
1
, Kong Xiang-Ming
1
, Xu Guo-Zhi
2
, Yang
Jiang-Ming
1
. The QingHai Provincial Hospital of Traditional Chinese Medicine, Xining,
Qinghai,, P.R.China
1
, The QingHai Provincial Hospital of Traditional Chinese Medicine, Xining,
Qinghai,, P.R.China
2
.
This study investigate the effects of Bos mutus Przewalski blood on the survival rates and
blood gas changes of rats under decreased air pressure conditions. Methods: We created an
artificial high altitude hypoxia environment method to study its effects on rats. Survival rate: fifty
rats were randomly divided into five groups. After treatment (rats were given Bos mutus
Przewalski blood dried powder), each rat was set into a vacuum evaporation box, in which the air
pressure was decreased gradually by vacuum pump until equal to that of 9000m altitude. The
vacuum box was opened when half of the control rats had died. The survival rates of the five
groups were then calculated separately. The survival rate of control group was 40%, while in the
large dosage group, moderate dosage group and small dosage group it was 90%, 80% and 80%,
respectively. There was significant difference between the treatment groups and the control group
