children living at 3500-4200m, ages 1-2.5 years as the controls were also observed with MRI.
The MRI of all patients showed right ventricular hypertrophy and right ventricular enlargement
compared with the four controls, the RVAWs and RVAWd were 7.34±0.81mm vs. 3.58±0.02mm
and 5.31±1.05mm vs. 1.98±0.12mm, respectively, mean±SD, p<0.001. In the 8 patients, LVPWs
was 6.18±0.96mm, and LVPWd was 4.08±0.83mm. One case showed left ventricular
hypertrophy, and LVPWd was 6mm. In the healthy group, LVPWs was 5.62±0.52mm and
LVPWd was 3.68±0.30mm. All HAHD patient's IVS was straight or bulged toward the left
ventricle; IVSs was 4.72±1.29mm, and IVSd was 3.45±0.89mm. In one HAHD case the IVS
showed hypertrophy, and the IVSd was 5.6mm. The IVSs of healthy children was 4.78±0.87mm,
and the IVSd was 3.17±0.46mm. All HAHD patients showed pulmonary artery enlargement. The
PA in all patients was obviously enlarged compared with the PA in controls (17.0±1.3mm vs.
12.15±0.51mm, respectively, p<0.001). In conclusion, right ventricular hypertrophy and
pulmonary artery enlargement were major characteristics of High-Altitude Heart Disease
examined by MRI. Some patients showed left ventricular and interventricular septal hypertrophy.
MRI is a new effective method for the diagnosis of High-Altitude Heart Disease.
66.
A COMPARATIVE STUDY OF PULMONARY FUNCTIONAL IMAGING IN HEALTHY
TIBETAN AND HAN YOUTH USING SPIRAL CT TECHNIQUE. Bao Hai-Hua
1
, Ma Li-
Gong
1
, Li Wen-Fang
1
, Zhao Xi-Peng
1
, Wu You-Seng
1
, Ge Ri-Li
2
. Dept. CT, Affiliated Hospital
of Qinghai Medical College, Xining, China
1
, Research Center for High Altitude Medicine,
Qinghai Medical College, Xining, China
2
.
The purpose of this study was to investigate the difference in lung capacity between healthy
Tibetan and Han youth. Twenty healthy Tibetans living at 3500-4500m and twenty healthy Han
living at sea level (each group contained 10 male and 10 female subjects), with a mean age of 22
yrs., were recruited in this study. We determined and compared the levels of lung capacity and
pulmonary function of the two groups using spiral CT functional imaging and pulmonary
function tests. CT scanning and pulmonary function tests (PFT) were performed on the same day.
Spiral CT scans were acquired at full inspiration(Vin) and full expiration(Vex) from the lung
bases to lung apices with 120KV_135mA, 10mm slice thickness, pitch 1.5 reconstructed by
10mm slice thickness and standard algorithm. The Tibetan's Vin and Vex was 4.99±1.17L and
3.22±0.85L, respectively. The Han's Vin and Vex was 4.50±1.24L and 2.55±0.77L, respectively.
The total lung capacity (TLC), residual volume (RV) and diffusion of lung for carbon monoxide
(DLco) in the Tibetans were 5.61±1.12L, 1.76±0.06L and 15.12±3.07 mmol/min/kPa/L,
respectively. In the Han the TLC, RV and DLco were 5.10±0.98L, 1.45±0.42L and 10.40±2.94
mmol/min/kPa/L, respectively. In all subjects there was good correlation between the Vin and
TLC as well as between Vex and RV_r=0. 788, p_0.001, r=0.527, respectively, p_0.001). The
Tibetan's Vin showed a closer correlation with DLco of the PFT than did the Han_r=0.848,
p_0.001, r=0.455, p_0.05). There were no significant differences in Vin and TLC between
Tibetans and Han, whereas there were obvious differences in Vex and RV between Tibetans and
Han_p_0.05). Spiral CT scanning had a good correlation with TLC, RV and DLco of the PFT.
There was no difference in lung volume between Tibetan and Han whereas residual capacity and
DLco of the Tibetans were larger than those of the Han. In conclusion, full inspiration (Vin) and
full expiration (Vex) CT scans provide an evaluation of pulmonary function.
67.
EFFECTS OF INTERMITTENT HYPOXIA TRAINING ON MID-LONG DISTANCE
RUNNERS LIVING AT ALTITUDE . Liu Haiping
1
, Hu Yang
2
. Qinghai Sports Science
Institute
1
, Beijing Sports University
2
.
With altitude training developing, intermittent hypoxia training has also developed. In this
experiment, all subjects (native plateau athletes`) were randomly assigned to control group(10
players) and hypoxia group(10 players). The hypoxia group performed four weeks intermittent
hypoxia training, living in a hypobaric chamber eight hours (10:00pm-6:00am) every day and
trained at 2260m above sea level. The control group lived and trained at 2260m . Both groups
