patients, there were 30,197 patients (68.38%) with inflammatory disease in upper gastroinstinal
tract, 8,366 patients with peptic ulcer (18.95%), 1,908 patients with carcinomatosis of upper
gastrointestinal tract (4.32%), 237 patients with upper gastrointestinal benign tumor (0.52%), 474
patients with gastroduodenal polyp (1.08%), 1,035 patients with esophageal varicosity (2.34%),
and 1,941 patients with cases of other disorders (4.41%). According to the amount of upper
gastrointestinal disease in this group the incidence in decreasing order of frequency was
inflammation, ulcer and carcinoma. In conclusion, the incidence in males was higher than that of
females. The incidence in Tibetans was higher than that in Han. In Tibetans, inflammatory
disease in the upper gastroinstinal tract and ulcer were common diseases whereas carcinoma was
uncommon. The inhospitable climate, poor socioeconomic status, Tibetan daily lifestyle, and
poor hygiene conditions in the home probably play major roles in promoting the above diseases.
293.
EFFECT OF HYPOXIA ACCLIMATION ON MICROCIRCULATION OF HAMSTER
CHEEK POUCH WITH SEVERE FROSTBITE. Yang Zeng-Ren
1
, Liu Jia-Ying
2
, Yan Pei-Hua
2
.
Institute of Hygiene and Environmental Medicine, Academy of Military Medical Sciences, Ti
1
,
Institute of Hygiene and Environmental Medicine, Academy of Military Medical Sciences,
Tianjin
2
.
Objective: Changes in microcirculation status of cheek pouches in acute microcirculation
poxia and hypoxia acclimation hamsters before and after frostbite were observed for the purpose
of going further into the cause of reducing body ability to resist frostbite after hypoxia
acclimation. Methods: Hamsters were divided randomly into three groups: control (C), acute
hypoxia (A) and hypoxia acclimation (H). After the hamsters of group H were trained at
simulated hypoxia for 4 w, the microcirculation of hamsters in each group was observed. Then
the cheek pouches were frozen and thawed which lead to severe frostbite, and the
microcirculation was observed for 2 h continuously. Results: Before frostbite, the changes of
deeper color of blood, slower blood flow velocity and RBC accumulation in microcirculation in
group H, were severe than those in group C and A markedly. When the cheek pouches were
frozen, their blood flow was stasis. After the frozen cheek pouches were malted, their
microcirculation blood stream in pink color appeared again in arterioles, and then flowed in
venues slowly, and several seconds late the flow accelerated suddenly and the abnormal blood
color in light and deep became normal gradually. Meanwhile, RBC accumulation and a larger
amount of white and transparent thrombi appeared in blood flow. As the blood flow impacted,
most thrombi disappeared within 10 min after frostbite, and the following phenomenon could be
seen: the blood flowed slowly and fast, forward and backward by turns, or flow and stasis in turn,
and the micro vessels were systolic. At 1 h after frostbite, the microcirculation status worsened
gradually in most hamsters, improved in a few of them. The micro vessels contracted, dilated or
blocked, the blood flow slowed or stasis, the WBC adhered or rolling, RBC accumulation and so
on. At 2 h after frostbite, the microcirculation of each group worsened evidently: WBC escaped
from microvessels, venues dilated and arterioles contracted, microvessels emboli zed with mixed
thrombi or there was no blood reflow in microvessels. Those changes were severe in group H
than those in group C and A significantly. Conclusion: In this experiment, the microcirculation in
cheek pouch of hamster in group H was worsened caused by hypoxia acclimation, which may be
related to the increase in RBC numbers. After frostbite, the microcirculation status in group H
exacerbated evidently, which was unfavorable for the recovery of frostbitten tissue, and was one
of the main causes reducing the ability to resist frostbite.
294.
THE STUDY OF THE STATE OF WORK AND NUTRITION FOR THE HIGH ALTITUDE
AREA WORKERS. Shije Zhang
1
, Hongrong Ji
1
, Chunco Shi
1
, Yue Li
1
. CDC of Qinghai
Province, China
1
.
Background: Because of the low pressure and lack of oxygen, workers in high altitude areas
suffer a physiology burden and it's hard to recover from work, compared to work at low altitude..
Hence, it's very important to have some research on the state of nutrition for workers working in
