Proteus, S.A. 70, allée Graham Bell
Parc Georges Besse 30000 - Nimes France
Tel : +33(0)466 70 64 64 Fax : +33(0)466 70 64 60
E-mail :
info@proteus.fr
Web site :
www.proteus.fr
For developing new processes combining synthetic chemistry and
biotechnology, we use the optimal conditions defined by process
developers as a starting point. We then
tailor the biocatalyst to that
process
.
This approach requires a
multidisciplinary team
to be successfully
addressed. An integrated platform has been built where chemists,
biochemists, microbiologists, molecular biologists and bioprocess
experts team up to
rapidly design robust and scalable routes
to the
target compounds, e.g. chiral APIs or intermediates.
Every characteristics of the molecules (stability, solubility, quality,
racemization conditions, downstream separation or purification
processes contemplated, cost, quality and availability of the raw
materials...) as well
as the constraints of the industrial process
(temperature, pH, salt concentration, solvents...) are integrated. High
throughput and high content screening assays are designed, calibrated
and implemented in Protéus state-of-the art HTS facilities to rapidly
identify and/or engineer the appropriate biocatalyst and
make it
available for manufacturing
.
Process specifications
as a guideline
Customer satisfaction
In-house expertise in Intellectual Property
A full time dedicated team specialized in
intellectual property and competitive
intelligence is supporting the project leaders
for targeting freedom to operate for our
partners and for securing the new intellectual
property generated.
Unique biodiversity
including a broad collection
of extremophiles
Proprietary technologies
PhenomicsTM in vitro cell-free gene expression
CLIPS-OTM chemistry for functional assays
L-Shuffling TM for directed evolution
using gene shuffling.
Protéus' strength comes from its integrated multidisciplinary platform
which includes
proprietary technologies
and dedicated teams of
skilled professionals with rich experience in
synthetic organic
chemistry, biocatalysis, microbiology, protein engineering and
protein expression.
The combination of a unique collection of biodiversity (including a broad
collection of extremophiles) with proprietary technologies for functional
genomics, high throughput and high content screening, recombinant
protein expression, functional assays, protein engineering and directed
evolution in conjunction with our bioprocess expertise and capabilities,
makes Protéus
a leading company in the discovery and
development of novel biocatalysts
.
Protéus bioprocessing facilities include capabilities for the production of
novel biocatalysts at laboratory and pilot scale and for transferring
complete process books for
immediate production of commercial
scale launch quantities.
Quick design of chemo-
biocatalytic routes
Our aim is to
provide to our partners
the products that give them an
additional competitive edge.
Integration of advanced biotechnologies offers unprecedented
opportunities to the development of
highly efficient and selective
processes for production of fine and specialty chemicals
.
Biocatalysis also plays a key role in
sustainable development
as
biotechnology-based processes consume much less energy, use lower
amounts of non-renewable resources and produce minimal waste.
Protéus has been successfully partnering with leading companies , e.g.
Aventis, Henkel, Degussa, etc. in many different fields of application.
Learn more about how Protéus can accelerate your business
development projects and submit your inquiry to
info@proteus.fr
.
Proteus'
stringent confidentiality policy
will apply to your inquiry.
Exclusive know-how
microbiology
molecular biology
protein engineering
biochemistry
protein expression
chemistry
bioprocess (fermentation
& downstream processing)
Tailoring biocatalysts to processes
To fulfil this mission, Protéus has
established a research center integrating
all the skills and capabilities required,
including chemistry and bioprocess
(fermentation & downstream processing)
