Proteus, S.A. 70, allée Graham Bell
Parc Georges Besse 30000 - Nimes France
Tel : +33(0)466 70 64 64 Fax : +33(0)466 70 64 60
E-mail :
info@proteus.fr
Web site :
www.proteus.fr
Protéus has an extensive experience in
developing
production processes of recombinant proteins
. Proprietary
technologies and exclusive know has been developed and
offered to selected clients within the frame of exclusive
partnerships targeting certain application. Protein expression at
Protéus benefits from this experience acquired with leading
industrial partners. A wide variety of proteins have been
successfully expressed, from biocatalysts for the synthesis of
chiral APIs to therapeutical proteins for pharmacological pre-
clinical investigation.
New !
Today, PSI offers the access to the same technology
platform and expertise for expressing your own genes.
The outstanding offering of Protéus for protein expression
includes :
Microbial and cell-free
expression (including the
proprietary cell-free in vitro PhenomicsTM system) ;
Libraries of
prokaryotic and eukaryotic hosts
, and
expression
vectors
;
High throughput
functional expression of gene libraries
for screening purpose (µL scale) ;
Fermentation capabilities for
pilot-scale expression
(3 L
to 100 L scale) ;
Design of expression systems suited for genes from a
variety of phylogenetic origins ;
Molecular biology expertise for engineering expression
systems to
improve production yield and product
performances
;
Gene shuffling proprietary technology
for improving and
fine tuning the functional characteristics of the proteins
expressed ;
Optimization of bioprocess, including
fermentation
and
downstream processing
;
Endotoxin-free
expression.
Protéus has an experienced team of Process Development
scientists whose goal is to
establish cost-effective, robust
and scaleable biologic manufacturing solutions
. We focus
on development strategies that maximize expression and yield
while meeting product specifications. Product can be delivered
at the 3 L100L scale to quickly start pre-clinical or pre-
industrial evaluation.
With our extensive experience in process development for
production of recombinant proteins, we help accelerate
timelines through a fully integrated approach from
bioengineering and development through pilot scale production.
Our comprehensive bioengineering, fermentation, recovery,
purification and analytical tools and skills enable product yields
optimization. Dedicated project leaders ensure smooth
operations and creates a strong synergy between the different
skills. They coordinate each project
and insure on-time
delivery of quality products and processes.
Recombinant
Protein Expression
and Process
Development
More Options for
Protein
Optimization & Production
We offer proprietary cell-free expression
systems and microbial expression systems
such as E. coli, Bacillus, Pseudomonas,
yeast and fungi and a comprehensive
downstream processing expertise
From lab to pilot
scale expression
and industrial
scale up process
design
Now available as a service.
Call PSI, the dedicated service
business unit of Protéus
to know more.
