5
HIGASHIDE, OCT and Angiography of Toxocara Granuloma
leakage surrounded by a hypofluorescent rim (Fig. 2). The macular
lesion remained stable thereafter for six months.
The
Toxocara granuloma in our case had a subretinal extension in
the OCT images and resembled an idiopathic choroidal
neovascularization (CNV) in the active stage.
3,4
The granuloma
responded to the systemic steroid and anthelminthic therapy, ceased
being exudative, and was confined below the RPE in the OCT images.
Angiography revealed a hypofluorescent rim surrounding the CNV-like
reticular hyperfluorescence in the lesion. The transition to a sub-RPE
location and the emergence of a hypofluorescent rim are characteristic
OCT
4
and indocyanine green angiographic
5
findings, respectively, of
idiopathic CNV in the involution stage and indicate the envelopment
of the CNV by the RPE. Thus, RPE proliferation may play an important
role in the regression of a granuloma as well as a CNV.
In conclusion, subretinal Toxocara granuloma can have a similar
presentation as idiopathic CNV in OCT images and angiograms and,
therefore, should be included in the differential diagnosis of the
idiopathic CNV.
