4
HIGASHIDE, OCT and Angiography of Toxocara Granuloma
the late phase (Fig. 1).
A clinical diagnosis of ocular toxocariasis was made from a
positive history of repeated ingestion of raw liver that is regarded
to be a significant risk factor of Toxocara infestation,
2
the
detection of serum antibody to antigens from second-stage larvae of
Toxocara canis by enzyme-linked immunosorbent assay, and the
exclusion of other ocular conditions causing exudative macular
lesions.
She was started on oral prednisone (30 mg daily, tapered over 2
months) and diethylcarbamazine (100 mg daily for 3 days, 300 mg daily
for 3 days, followed by 300 mg once a week for 8 weeks). The serous
retinal detachment gradually decreased and the macular lesion became
smaller and more clearly bordered with pigment.
Three month after the first examination, her visual acuity had
improved to 20/20. In OCT, the macular lesion had decreased to a
smaller elevation covered by the RPE without signs of retinal edema
(Fig. 2). Fluorescein and indocyanine green angiography disclosed
an oval-shaped, reticular hyperfluorescent lesion with minimal dye
