American Journal of Ophthalmology AJO 2892 Page 14
Page 14
Mimura T, Relationship between HLA and retinopathy in patients with type 1 diabetes
Table 2. HLA-A, -B, and -C Antigen Frequencies (%) in Each Group
Control
group
non-DR
group
PDR
group
2
P value
Relative
Risk
A1 0
(0.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
A2 18
(36.0)
16
(32.0)
5 (16.7)
2.277
NS
0.425
A11 9
(18.0)
10
(20.0)
6 (20.0)
0.000
NS
1.000
A24 (9)
30 (60.0)
36 (72.0)
22 (73.3)
0.017
NS
1.069
A26 (10)
11 (22.0)
11 (22.0)
9 (30.0)
0.640
NS
1.519
A28 0
(0.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
A30 (19)
0 (0.0)
1 (2.0)
0
(0.0)
0.608
NS
0.000
A31 (19)
9 (18.0)
5 (10.0)
4 (13.3)
0.209
NS
1.385
A33 (19)
7 (14.0)
15 (30.0)
6 (20.0)
0.969
NS
0.583
B7 5
(10.0)
4
(8.0)
2
(6.7)
0.048
NS
0.821
B13 1
(2.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
B17 1
(2.0)
3
(6.0)
1
(3.3)
0.281
NS
0.540
B27 0
(0.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
B35 10
(20.0)
12
(24.0)
8 (26.7)
0.071
NS
1.152
B37 1
(2.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
B39 3
(6.0)
1
(2.0)
0
(0.0)
0.608
NS
0.000
B40 1
(2.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
B44 (12)
8 (16.0)
13 (26.0)
7 (23.3)
0.071
NS
0.866
B46 5
(10.0)
5
(10.0)
0
(0.0)
3.200
NS
0.000
B48 2
(4.0)
3
(6.0)
0
(0.0)
1.870
NS
0.000
B51 (5)
9 (18.0)
2 (4.0)
0
(0.0)
1.231
NS
0.000
B52 (5)
10 (20.0)
6 (12.0)
6 (20.0)
0.941
NS
1.833
B54 (22)
9 (18.0)
13 (26.0)
7 (23.3)
0.071
NS
0.866
B55 (22)
2 (4.0)
3 (6.0)
3 (10.0)
0.432
NS
1.741
B56 (22)
2 (4.0)
2 (4.0)
2
(6.7)
0.281
NS
1.714
B59 2
(4.0)
4
(8.0)
3 (10.0)
0.094
NS
1.278
B60 (40)
4 (8.0)
2 (4.0)
0
(0.0)
1.231
NS
0.000
B61 (40)
12 (24.0)
17 (34.0)
9 (30.0)
0.137
NS
0.832
B62 (15)
6 (12.0)
3 (6.0)
10 (33.3)
10.293
.0020
7.833
B67 1
(2.0)
2
(4.0)
0
(0.0)
1.231
NS
0.000
B70 1
(2.0)
2
(4.0)
0
(0.0)
1.231
NS
0.000
B75 1
(2.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
Cw1 15
(30.0)
21
(42.0)
15 (50.0)
0.485
NS
1.381
Cw3 24
(48.0)
14
(28.0)
8 (26.7)
0.017
NS
0.935
Cw4 6
(12.0)
2
(4.0)
8 (26.7)
8.808
.0048
8.727
Cw5 1
(2.0)
1
(2.0)
0
(0.0)
0.608
NS
0.000
Cw6 1
(2.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
Cw7 10
(20.0)
9
(18.0)
8 (26.7)
0.842
NS
1.657
Cw8 0
(0.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
Cw9 3
(6.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
Cw10 8
(16.0)
0
(0.0)
0
(0.0)
0.000
NS
1.000
Comparisons between the PDR group and the non-DR group are shown. Numbers in parentheses
are percentages. NS = not significant.
