American Journal of Ophthalmology AJO 2892 Page 13
Page 13
Mimura T, Relationship between HLA and retinopathy in patients with type 1 diabetes
DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites. Diabetes
1990;40;759-763.
Table 1. Clinical Profile of the Control Group, non-DR Group, and PDR Group
P
Control
group
non-DR
group
PDR
group
Control
v.s.
non-DR
Control
v.s.
PDR
non-DR
v.s.
PDR
Number of patients
50
50
30
Male /
Female
17 (34%) /
33 (66%)
22 (44%) /
28 (56%)
9 (30%) /
21 (70%)
NS* NS* NS*
Age (years)
26.7
± 5.1
26.4
± 4.4
27.3
± 5.3
NS** NS** NS**
Duration of diabetes at the
time of the study (years)
-
15.2
± 5.1
16.4
± 4.8
- -
NS**
Age at the diagnosis of
diabetes (years)
-
16.5
± 5.2
16.8
± 5.6
- -
NS**
Age at the diagnosis of
diabetic retinopathy
(years)
- -
23.8
± 4.2
- - -
HbA
1C
(%): average for 10
years
-
8.5
± 1.2
8.7
± 1.2
- -
NS**
Hypertension (%)
0 (0.0%)
2 (4.0%)
3 (10.0%)
NS*
.049*
NS*
Renal didease (%)
0 (0.0%)
4 (8.0%)
11 (36.7%)
NS*
<.0001*
.0022*
Neurophysiological
neuropathy (%)
0 (0.0%)
8 (16.0%)
10 (30.0%)
.0029* <.0001*
NS*
Positive family history of
diabetes mellitus (%)
0 (0.0%) 17 (34.0%)
14 (46.7%) <.00001* <.00001* NS*
Number of patients or mean ± standard deviation.
NS = not significant.
*
= chi-square test of independence or Fisher's exact probability test.
**
= unpaired t-test.
