25
Freeman, Cataract Surgery and Age-Related Macular Degeneration
Table 6. Analysis of early AMD 1 associated with time since cataract surgery or presence
of severe cataract at clinical exam for SEE, BES*.
Variable SEE
Early AMD 1
n=3912
OR 95% CI
BES
Early AMD 1
n=8656
OR 95% CI
SEE and BES
Early AMD 1
n=12568
OR 95% CI
Neither severe cataract nor surgery
Presence of severe cataract
Surgery < 5 years ago
Surgery >=5 years ago
1.0 reference
1.2 0.9-1.7
1.2 0.9-1.6
1.7 1.1-2.4
1.0 reference
0.5 0.2-1.4
0.7 0.4-1.4
0.7 0.4-1.4
1.0 reference
1.1 0.8-1.5
1.2 0.9-1.5
1.3 1.0-1.7
*Adjusted for age, sex, smoking, race, and study (SEE and BES combined). Generalized estimating
equations were used to estimate the standard errors in order to account for the correlation between eyes.
Early AMD 1: drusen >=64 microns, hyperpigmention, or nongeographic atrophy
Severe Cataract defined as grade 4 or higher on photographs in SEE and PVER, and by the clinical
determination of cataract as a cause of visual impairment or blindness in BES.
Abbreviations
SEE: Salisbury Eye Evaluation
BES: Baltimore Eye Survey
OR: odds ratio
CI: confidence interval
AMD: age-related macular degeneration
