23
Freeman, Cataract Surgery and Age-Related Macular Degeneration
Table 4. Analysis of late AMD* associated with previous cataract surgery or presence of
severe cataract at time of clinical exam for SEE, BES, PVER.
Variable SEE
n=4627 eyes
late AMD
OR 95% CI
BES
n=7364 eyes
late AMD
OR 95% CI
PVER
n=9477 eyes
late AMD
OR 95% CI
Combined
n=21460
late AMD
OR 95% CI
Neither cataract nor surg
Severe cataract present
Previous cataract surg
1.0 reference
1.3 0.6-2.8
1.3 0.7-2.4
1.0 reference
2.1 0.3-17.8
2.6 0.9-7.5
1.0 reference
1.3 0.5-2.9
1.9 0.9-4.1
1.0 reference
1.4 0.8-2.4
1.7 1.1-2.6
*Late AMD defined as choroidal neovascularization, geographic atrophy, or as a cause of blindness as
determined by photographs in SEE, and by clinical exam in PVER.
Individual studies adjusted for age, sex, smoking, race (SEE and BES only). Combined analyses
adjusted for age, sex, smoking, race (Caucasian, non-Caucasian), and study.
Severe Cataract: nuclear=4, cortical>=8/16, or any PSC opacity as determined from photographs for
SEE and PVER, and by visual impairment or blindness attributed to cataract as determined by clinical
exam in BES.
Abbreviations
SEE: Salisbury Eye Evaluation
PVER: Proyecto VER
BES: Baltimore Eye Survey
OR: odds ratio
CI: confidence interval AMD: age-related macular degeneration
